Association of pregestational obesity with anemia during pregnancy: A literature review

Relevance: Оbеse pregnant women have а mild inflammatory response associated with hepcidin overexpression. Inflammation affects iron metabolism by increasing levels. Obesity and anemia are serious problems worldwide; expectant mothers often suffer from these conditions. Gravidas obesity tend to gain more weight during pregnancy than gravidas normal body mass index. before is a high risk in pregnancy, including hypoferremia due deficiency, which already common between mother their neonates. This review considers obesity-associated mediator activation as potential primary cause of deficiency (ID) or (IDA) obese women.The aimed summarize the current studies reporting measurement molecular markers mediators pregestational obesity. Methods: included all types publications English Russian on published March 2012 2022. The literature search was performed Medline, Scopus, Web Science, Google Scholar, PubMed, CyberLeninka databases following keywords: “pregnancy,” “iron deficiency,” “anemia,” “overweight,” “obesity,” “inflammation,” “body index.”Results: assesses whether obesity-induced inflammation may contribute increased incidence ID/IDA women. Despite numerous studies, effect maternal remains unclear. Iron status against considered. PR-pregnancy carries greater developing postnatal period for baby. Conclusions: Thus, careful study levels trimester required. introduction clearly defined procedures valuation antenatal postpartum consultations necessary.